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PERTUSSIS VACCINE EFFECTIVENESS AFTER MASS IMMUNIZATION OF HIGH SCHOOL STUDENTS IN AUSTRALIA

Rank, Claudia MIPH*; Quinn, Helen E. PhD†; McIntyre, Peter B. MB, PhD†

Pediatric Infectious Disease Journal:
doi: 10.1097/INF.0b013e318185608e
Brief Reports
Abstract

Vaccine effectiveness in the first large-scale use of adolescent pertussis vaccine in Australia was evaluated by the screening method. Vaccine effectiveness was 78.0% (95% CI: 60.7–87.6%) for all study cases (n = 167), increasing to 85.4% (95% CI: 83.0–87.5%) for laboratory-confirmed cases (n = 155). Effectiveness should be comparable in settings with similar programs, such as the United States and Canada.

Author Information

From the *The University of Sydney, New South Wales, Australia; and †National Centre for Immunisation Research and Surveillance of Vaccine Preventable Diseases, The Children's Hospital at Westmead, New South Wales, Australia.

Accepted for publication July 1, 2008.

NCIRS is supported by The Australian Government Department of Health and Ageing, the NSW Department of Health, and The Children's Hospital at Westmead.

Address for correspondence: Peter B. McIntyre, MB, PhD, National Centre for Immunisation Research and Surveillance of Vaccine Preventable Diseases (NCIRS), The Children's Hospital at Westmead, Locked Bag 4001, Westmead, NSW 2145, Australia. E-mail: peterm@chw.edu.au.

© 2009 Lippincott Williams & Wilkins, Inc.