We aimed to determine patient characteristics, treatment challenges, and adherence outcomes according to orphanhood status in a prospective cohort of 101 HIV+ children in rural Uganda. Orphans were older at antiretroviral initiation (P = 0.0008) and more likely to be WHO stage-4 (P = 0.03) than nonorphans. More attention to improving access to antiretrovirals in pediatric populations, especially orphans, is needed.
From the *Joint Clinical Research Centre, Mbale, Uganda; †The Mbale Project (M-PROJ), Mbale, Uganda; ‡Joint Clinical Research Centre, Kampala, Uganda; §Faculty of Health Sciences, Simon Fraser University, Burnaby, BC, Canada; ¶The Ottawa Hospital, Ottawa ON, Canada, and ∥British Columbia Centre for Excellence in HIV/AIDS, Vancouver, BC, Canada.
Accepted for publication June 27, 2008.
Address for correspondence: Edwards Mills, PhD, MSc, BC Centre For Excellence in HIV/AIDS, St. Paul's Hospital, 1081 Burrard Street, Vancouver, BC, Canada. E-mail: firstname.lastname@example.org.