Three cases of Clostridium difficile-associated disease in children were detected within a short time interval. Intensive therapy was required in 2 cases with colectomy in one of them. One of the severe cases was community-acquired. Two patients had underlying diseases (Hirschprung disease, Down syndrome) and also tested positive for enteric viruses (rotavirus, calicivirus).
From the *Departments of Infectious Diseases and †Pediatric Surgery, University Medical Centre Ljubljana; ‡Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana; and §Institute of Public Health Maribor, Faculty of Medicine, University of Maribor, Maribor, Slovenia.
Accepted for publication March 3, 2008.
Address for correspondence: Marko Pokorn, MD, MSc, Department of Infectious Diseases, University Medical Centre Ljubljana, Ljubljana, Slovenia. E-mail: firstname.lastname@example.org.
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