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SEVERE CLOSTRIDIUM DIFFICILE—ASSOCIATED DISEASE IN CHILDREN

Pokorn, Marko MD, MSc*; Radšel, Anja MD*; Čižman, Milan MD, PhD*; Jereb, Matjaž MD, PhD*; Karner, Primož MD*; Kalan, Gorazd MD, MSc†; Grosek, Štefan MD, PhD†; Andlovic, Alenka MD‡; Rupnik, Maja PhD§

Pediatric Infectious Disease Journal: October 2008 - Volume 27 - Issue 10 - pp 944-946
doi: 10.1097/INF.0b013e3181723d32
Brief Reports

Three cases of Clostridium difficile-associated disease in children were detected within a short time interval. Intensive therapy was required in 2 cases with colectomy in one of them. One of the severe cases was community-acquired. Two patients had underlying diseases (Hirschprung disease, Down syndrome) and also tested positive for enteric viruses (rotavirus, calicivirus).

From the *Departments of Infectious Diseases and †Pediatric Surgery, University Medical Centre Ljubljana; ‡Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana; and §Institute of Public Health Maribor, Faculty of Medicine, University of Maribor, Maribor, Slovenia.

Accepted for publication March 3, 2008.

Address for correspondence: Marko Pokorn, MD, MSc, Department of Infectious Diseases, University Medical Centre Ljubljana, Ljubljana, Slovenia. E-mail: marko.pokorn@mf.uni-lj.si.

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© 2008 Lippincott Williams & Wilkins, Inc.