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Flexible Bronchoscopy for Diagnosis and Follow Up of Childhood Endobronchial Tuberculosis

Cakir, Erkan MD; Uyan, Zeynep Seda MD; Oktem, Sedat MD; Karakoc, Fazilet MD; Ersu, Refika MD; Karadag, Bulent MD; Dagli, Elif MD

Pediatric Infectious Disease Journal: September 2008 - Volume 27 - Issue 9 - pp 783-787
doi: 10.1097/INF.0b013e318170fccc
Original Studies

Background: In this study, our aim was to determine the clinical and bronchoscopic outcome of the endobronchial tuberculosis (ETB).

Methods: Patients with suspected tuberculosis (TB) or TB patients with an inadequate response to 8 weeks of antituberculosis treatment were enrolled in the study.

Results: Seventy patients were included to the study and 118 flexible bronchoscopies were performed. ETB was present in 33 (47%) patients. There was isolated compression in 14 cases, caseous lesions in 13, granuloma formation in 6, polypoid lesions in 2, adenopathy protrusion in 1, and mucosal erosion in 1 case. The mean duration of bronchoscopic resolution of endobronchial lesions was 5.50 ± 2.74 months. Mycobacterium tuberculosis was isolated from gastric lavage in 10% and from bronchoalveolar lavage in 12.8% of 70 cases. When both of the procedures were performed concurrently, the isolation rate increased to 20%. Transient hypoxia resolving with nasal O2 was observed in 3 patients as a complication of bronchoscopy.

Conclusions: Bronchoscopy offered a safe and rapid means of confirming the diagnosis of ETB.

From the Division of Pediatric Pulmonology, Marmara University, Istanbul, Turkey.

Accepted for publication February 27, 2008.

None of the authors have any conflict of interest.

Address for correspondence: Erkan Cakir, MD, Sumko Sitesi M 1 B Blok D: 22 Kozyatagi Kadikoy, Istanbul, Turkey. E-mail: erkancakir1@yahoo.com.

© 2008 Lippincott Williams & Wilkins, Inc.