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Human Papillomavirus DNA Detected in Breast Milk

Sarkola, Marja MD*†; Rintala, Marjut MD, PhD†; Grénman, Seija MD, PhD†; Syrjänen, Stina DDS, PhD*

Pediatric Infectious Disease Journal:
doi: 10.1097/INF.0b013e318169ef47
Brief Reports
Abstract

Human papillomavirus (HPV) testing of 223 breast milk samples 3 days postpartum was performed with polymerase chain reaction, hybridization, and sequencing. HPV-16-DNA was detected in 4.0% of the samples. HPV carriage in the breast milk was not correlated with mother's oral or cervical HPV-status or the demographic data. Oral HPV-infection of the spouse at month 6 and 12 postpartum was statistically significantly associated with HPV carriage in the breast milk.

Author Information

From the *MediCity Research Laboratory and Department of Oral Pathology, Institute of Dentistry, Faculty of Medicine, University of Turku; and †Department of Obstetrics and Gynaecology, University Central Hospital, Turku, Finland.

Accepted for publication January 21, 2008.

This study was supported by Päivikki and Sakari Sohlberg Foundation, Helsinki, Finland and the Governmental Special Foundation for Turku University Central Hospital, Finland.

Address for correspondence: Stina Syrjänen, DDS, PhD, Department of Oral Pathology, Institute of Dentistry, Faculty of Medicine, University of Turku, Lemminkäisenkatu 2, FI 20520, Turku. E-mail: stina.syrjanen@utu.fi.

© 2008 Lippincott Williams & Wilkins, Inc.