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DISTRIBUTION OF STREPTOCOCCUS PNEUMONIAE SEROTYPES IN NASOPHARYNGEAL CARRIAGE AND IN INVASIVE PNEUMOCOCCAL DISEASE IN SAO PAULO, BRAZIL

Berezin, Eitan N. MD*; Cardenuto, Maria D. MD*; Ferreira, Leda L. MD†; Otsuka, Marcelo MD‡; Guerra, Maria L. MSci§; Brandileone, Maria Cristina C. PhD§

Pediatric Infectious Disease Journal: July 2007 - Volume 26 - Issue 7 - pp 643-645
doi: 10.1097/INF.0b013e3180616d0f
Brief Reports

To determine whether serotypes of S. pneumoniae isolated from the nasopharynx (NP) are representative of data from patients with invasive disease, we collected NP swab specimens from children, between 3 months and 5 years and obtained data from 105 children hospitalized with invasive disease. The prevalence of penicillin nonsusceptible strains in the NP carriage and invasive disease group was 16.4% and 17%, respectively, in the first period and 42% and 45% in the second period. The serotypes 23F, 6A, 14 and 19F were the most common in the NP study and 14, 1, 5 and 6B were the most common in invasive infections.

From the *Santa Casa S. Paulo University Hospital-Pediatrics Infectious Diseases Unit; †S. Paulo University Hospital; ‡Darci Vargas Children Hospital; and §Instituto Adolfo Lutz, S. Paulo, Brazil.

Accepted for publication March 22, 2007.

Address for correspondence: Eitan Berezin, Av Roberto Lorenz 482 S. Paulo, S. Paulo, Brazil, Cep 05611-050. E-mail: eberezin2003@yahoo.com.

© 2007 Lippincott Williams & Wilkins, Inc.