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SEROLOGIC EVIDENCE FOR REGIONAL DIFFERENCES IN PEDIATRIC CRYPTOCOCCAL INFECTION

Davis, Jennifer MD*; Zheng, Wang Yong PhD*; Glatman-Freedman, Aharona MD*; Ng, Josephine Anne Navoa MD†; Pagcatipunan, Marimel R. MD‡; Lessin, Herschel MD§; Casadevall, Arturo MD, PhD∥; Goldman, David L. MD*

Pediatric Infectious Disease Journal:
doi: 10.1097/INF.0b013e318047e073
Brief Reports
Abstract

Cryptococcus neoformans is present in areas contaminated with pigeon droppings. Unrecognized infections are hypothesized to occur commonly among immunocompetent individuals. We used serology to estimate prevalence of cryptococcal infection in immunocompetent children from 3 regions. Our results indicate unrecognized cryptococcal infections are extremely common in Bronx children, but uncommon in children from Dutchess County, NY and the Philippines.

Author Information

From the *Department of Pediatrics, Childrens Hospital at Montefiore Albert Einstein College of Medicine, Bronx, NY; †St. Luke's Medical Center, Quezon City, Philippines; ‡University of the Philippines College of Medicine and Philippine General Hospital, Manila, Philippines; §Childrens Medical Group, Poughkeepsie; and ∥Department of Medicine, Albert Einstein College of Medicine, Bronx, NY.

Accepted for publication February 8, 2007.

Address for correspondence: David L. Goldman, MD, Department of Pediatrics, Albert Einstein College of Medicine, 1300 Morris Park Ave., Bronx, NY 10461. E-mail: dgoldma@aecom.yu.edu.

© 2007 Lippincott Williams & Wilkins, Inc.