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Pediatric Infectious Disease Journal:
doi: 10.1097/INF.0b013e318047e073
Brief Reports

SEROLOGIC EVIDENCE FOR REGIONAL DIFFERENCES IN PEDIATRIC CRYPTOCOCCAL INFECTION

Davis, Jennifer MD*; Zheng, Wang Yong PhD*; Glatman-Freedman, Aharona MD*; Ng, Josephine Anne Navoa MD†; Pagcatipunan, Marimel R. MD‡; Lessin, Herschel MD§; Casadevall, Arturo MD, PhD∥; Goldman, David L. MD*

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Abstract

Cryptococcus neoformans is present in areas contaminated with pigeon droppings. Unrecognized infections are hypothesized to occur commonly among immunocompetent individuals. We used serology to estimate prevalence of cryptococcal infection in immunocompetent children from 3 regions. Our results indicate unrecognized cryptococcal infections are extremely common in Bronx children, but uncommon in children from Dutchess County, NY and the Philippines.

© 2007 Lippincott Williams & Wilkins, Inc.

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