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EFFECTIVENESS OF PNEUMOCOCCAL CONJUGATE VACCINE IN GREATER VANCOUVER, CANADA: 20042005

Bjornson, Gordean MBA*; Scheifele, David W. MD*; Bettinger, Julie PhD*; Patrick, David M. MD†; Gustafson, Larry MD‡; Daly, Patricia MD§; Tyrrell, Gregory J. PhD∥

Pediatric Infectious Disease Journal:
doi: 10.1097/INF.0b013e31803c56df
Brief Reports
Abstract

Active, population-based surveillance for invasive pneumococcal infections in Greater Vancouver (population 473,000 children) demonstrated a rapid, substantial decrease in incidence rates for children 6–23 months old with routine infant vaccination. In the subpopulation with best case ascertainment disease rates for 6–23 month olds decreased 84.6% (92.5% for vaccine serotypes).

Author Information

From the *Vaccine Evaluation Center, BC Children's Hospital, Vancouver; †BC Centre for Disease Control, Vancouver; ‡Fraser Health Authority, Surrey; §Vancouver-Coastal Health Authority, Vancouver, British Columbia; and the ∥National Centre for Streptococcus, Edmonton, Alberta, Canada.

Accepted for publication January 23, 2007.

Supported by a grant from Wyeth Pharmaceuticals Canada, Markham, Ontario.

Presented in brief at the 7th Canadian Immunization Conference, Winnipeg, Manitoba, December 3–6, 2006 (abstract P01).

Address for correspondence: David Scheifele, MD, Vaccine Evaluation Center, Room L427–4500 Oak Street, Vancouver, B.C., Canada V6H 3N1. E-mail: dscheifele@cw.bc.ca.

© 2007 Lippincott Williams & Wilkins, Inc.