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Pediatric Infectious Disease Journal:
doi: 10.1097/01.inf.0000219535.14201.1b
Brief Reports

CHILDHOOD EMPYEMA: LIMITED POTENTIAL IMPACT OF 7-VALENT PNEUMOCOCCAL CONJUGATE VACCINE

Fletcher, Margaret PhD, FRCPCH*; Leeming, John PhD†; Cartwright, Keith FRCPath‡; Finn, Adam PhD, FRCP‡; on behalf of the South West of England Invasive Community Acquired Infection Study Group

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Abstract

During 2003–2004, locally presenting pleural empyema cases in children increased 3-fold. Antigen analysis of empyema fluid identified Streptococcus pneumoniae in 27 of 29 cases for whom samples were available and capsular polysaccharide type 1 in 18 of these. Use of a conjugate vaccine without serotype 1 antigen would have had limited impact on this morbidity in our region.

© 2006 Lippincott Williams & Wilkins, Inc.

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