In a retrospective, population-based study, we estimated the age-specific incidence of invasive pneumococcal disease in Hong Kong between 1995 and 2004. The incidence rates per 100,000 were 18.3 (95% confidence interval [CI], 13.9–23.3) for children aged ≤2 years, 15.6 (95% CI, 12.8–18.6) for children aged ≤5 years and 1 (95% CI, 0.52–1.7) for children aged 6–14 years. The findings indicate a significant disease burden.
From the *University of Hong Kong, †Pamela Youde Hospital, Hong Kong SAR, China; ‡Global Medical Affairs, Wyeth, United States
Accepted for publication December 14, 2005.
Supported by research grants from the Health Care and Promotion Fund Committee of the Health, Welfare and Food Bureau of the Hong Kong SAR Government and from the University Development Fund Project-Research Centre of Emerging Infectious Diseases of the University of Hong Kong.
Address for correspondence: Pak-Leung Ho, FACP, Division of Infectious Diseases, Department of Microbiology, Queen Mary Hospital, The University of Hong Kong, Pokfulam Road, Pokfulam, Hong Kong SAR, China. Fax 852-2855-1241; E-mail firstname.lastname@example.org.