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Pediatric Infectious Disease Journal:
doi: 10.1097/01.inf.0000207492.97867.15
Brief Reports

Safety and Immunogenicity of Live Varicella Virus Vaccine in Children With Human Immunodeficiency Virus Type 1

Armenian, Saro H. DO*‡; Han, Jin Young MD, PhD*‡; Dunaway, Theresa M. RN†‡; Church, Joseph A. MD†‡

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Live varicella virus vaccine was administered to 10 stable human immunodeficiency virus type 1 (HIV-1)-infected children. Subjects were monitored for adverse reactions, HIV-1 plasma levels, CD4+ T cell counts and immune responses. The vaccine was well-tolerated. Varicella-zoster virus-specific lymphocyte proliferative responses were detected in all subjects by 4 weeks and in 9 of 10 subjects 1 year after vaccination.

© 2006 Lippincott Williams & Wilkins, Inc.


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