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Dubos, François MD†; Delattre, Pierre MD†; Demar, Magali MD‡; Carme, Bernard MD‡; Gendrel, Dominique MD§
We evaluated retrospectively the safety of mefloquine (25 mg/kg) for the curative treatment of uncomplicated Plasmodium falciparum malaria in 26 infants weighing <15 kg and managed during a 5-year period. Side effects were recorded in 30.8% of patients and consisted chiefly of mild and transient gastrointestinal symptoms. Mefloquine was safe in infants weighing <15 kg in our experience.
© 2004 Lippincott Williams & Wilkins, Inc.
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falciparum, infants, malaria, mefloquine, tolerance
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