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Pediatric Infectious Disease Journal:
Instructive Cases

Effect of Highly Active Antiretroviral Therapy on Cardiovascular Involvement in Children With Human Immunodeficiency Virus Infection

Plebani, Anna MD*; Esposito, Susanna MD*; Pinzani, Raffaella MD*; Fesslova, Vlasta MD†; Bojanin, Jelena MD*; Salice, Patrizia MD†; Rossi, Matteo MD*; Principi, Nicola MD*

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Abstract

The impact of highly active antiretroviral therapy (HAART) on cardiovascular involvement was evaluated in 38 vertically human immunodeficiency virus-infected children followed up for 5 years. This study demonstrates for the first time in a cohort of children the resolution of previous dilated cardiomyopathy after the start of HAART and the absence of cardiovascular events related to metabolic abnormalities during the period of its administration.

© 2004 Lippincott Williams & Wilkins, Inc.

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