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TRANSPLACENTALLY ACQUIRED IMMUNOGLOBULIN G ANTIBODIES AGAINST MEASLES, MUMPS, RUBELLA AND VARICELLA-ZOSTER VIRUS IN PRETERM AND FULL TERM NEWBORNS

Leineweber, Birgit M.D.*; Grote, Veit M.D. Urs; Schaad, B. M.D.; Heininger, Ulrich M.D.

Pediatric Infectious Disease Journal: April 2004 - Volume 23 - Issue 4 - pp 361-363
Brief Reports

IgG antibody values against measles, mumps, rubella and varicella-zoster virus in 71 full term and 101 preterm infants and their 152 mothers and the decay of maternally acquired antibodies during infancy were studied. Both magnitude of transplacental antibody passage and cord blood antibody values correlated with gestational age. After 6 months preterm infants born before 32 weeks of gestation had lost maternal antibodies.

University Children‘s Hospital Basel, Switzerland (BL, UBS, UH) University Children’s Hospital Munich, Germany (VG)

Accepted for publication Dec. 15, 2003.

*Current address: Department of Neonatology, Charité Vir-chow Klinikum, Humboldt University, Berlin, Germany.

Address for reprints: Professor Dr. Ulrich Heininger, Division of Pediatric Infectious Diseases, University Children’s Hospital Basel, P.O. Box, CH-4005 Basel, Switzerland.Fax 41-61-685-6012; E-mail Ulrich.Heininger@unibas.ch.

© 2004 Lippincott Williams & Wilkins, Inc.