Neonatal invasive group A streptococcal disease: case report and review of the literatureMIYAIRI, ISAO MD; BERLINGIERI, DOMINIC MD; PROTIC, JOHN MD; BELKO, JOHN MDThe Pediatric Infectious Disease Journal: February 2004 - Volume 23 - Issue 2 - p 161-165 doi: 10.1097/01.inf.0000109887.40636.07 Instructive Case Abstract Author Information We present a fatal case of neonatal invasive group A streptococcal disease and review of the literature. Twenty-four cases were early onset disease and were associated with concurrent maternal infection, respiratory distress, pneumonia, toxic shock-like syndrome and serotype M1. Fifteen cases were late onset disease associated with soft tissue infections and meningitis. Maternal carriage was identified as an important factor in neonatal group A streptococcal disease. From the Division of Pediatric Infectious Diseases (JB) and the Department of Pediatrics (IM, DB), Long Island College Hospital, Brooklyn, NY; and the Clinical Microbiology Laboratory and the Department of Pathology (JP), Beth Israel Medical Center, New York, NY. Accepted for publication Oct. 30, 2003. Address for reprints: Isao Miyairi, M.D., Department of Infectious Diseases, St. Jude Childrens Research Hospital, 332 N. Lauderdale St., Memphis, TN 38105. E-mail Isao.Miyairi@stjude.org. © 2004 Lippincott Williams & Wilkins, Inc.