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Successful treatment of foscarnet-resistant herpes simplex stomatitis with intravenous cidofovir in a child

Bryant, Penelope MRCPCH; Sasadeusz, Joe FRACP, PhD; Carapetis, Jonathan FRACP, PhD; Waters, Keith FRACP; Curtis, Nigel MRCPCH, PhD

Pediatric Infectious Disease Journal:
Instructive Case

A leukemic child developed recurrent herpes simplex virus lesions shortly after receiving a bone marrow transplant and while taking acyclovir. The isolate was resistant to acyclovir and foscarnet in vitro. The lesions responded to a course of cidofovir.

Author Information

From the Departments of Microbiology and Infectious Diseases (PB, JC, NC), Paediatrics (JC, NC) and Haematology and Oncology (KW), University of Melbourne, Royal Children’s Hospital, and Victorian Infectious Diseases Service, Royal Melbourne Hospital (JS), Parkville Victoria, Australia.

Accepted for publication April 26, 2001.

Reprints not available.

© 2001 Lippincott Williams & Wilkins, Inc.