Purpose: Airway clearance is an essential part of the management of cystic fibrosis (CF) as it facilitates clearance of viscous pulmonary secretions. This review aimed to determine the effect of autogenic drainage (AD) and assisted autogenic drainage (AAD) compared with no, sham, or other types of airway clearance in children with CF.
Summary of Key Points: Two pediatric randomized cross-over trials were identified on the use of AD in children with CF; no studies were available on the use of AAD. In one study AD had a positive influence on the Huang score, and is preferred over postural drainage in this population.
Conclusions and Recommendations: We could not determine the efficacy of AD and AAD in children with CF. We recommend the implementation of pediatric-specific randomized controlled trials with adequate sample sizes, appropriate clinical outcome measures, and analysis of adverse effects.
This review investigates the effect of autogenic drainage and assisted autogenic drainage compared with no, sham, or other types of airway clearance in children with cystic fibrosis.
Department of Health and Rehabilitation Sciences, Physiotherapy (Ms Corten), University of Cape Town, Observatory, South Africa; and School of Child and Adolescent Health, Paediatric Critical Care and Children's Heart Disease (Dr Morrow), University of Cape Town, Red Cross War Memorial Children's Hospital, Rondebosch, South Africa.
Correspondence: Lieselotte Corten, MSc, F45 Old Main Building, Grootte Schuur Hospital, Anzio Road, Observatory 7925, Cape Town, South Africa (firstname.lastname@example.org).
Grant Support: Ms Lieselotte Corten received the Margaret Roper Scholarship from the Division of Physiotherapy for her PhD studies at the University of Cape Town. The Department of Paediatrics and Child Health research award (University of Cape Town) provided funds to purchase articles for this review.
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Ms Lieselotte Corten was a PhD student at the Division of Physiotherapy, Department of Health and Rehabilitation Sciences, University of Cape Town, Observatory, Cape Town, South Africa, while writing this article.
The authors declare no conflicts of interest.