Pediatric Physical Therapy

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Pediatric Physical Therapy:
doi: 10.1097/PEP.0b013e31828a205f
Research Article

Reliability and Validity of the TIMPSI for Infants With Spinal Muscular Atrophy Type I

Krosschell, Kristin J. PT, DPT, MA, PCS; Maczulski, Jo Anne MA, OTR/L; Scott, Charles PhD; King, Wendy PT, BA; Hartman, Jill T. PT, DPT; Case, Laura E. PT, DPT, MS, PCS, C/NDT; Viazzo-Trussell, Donata PT, DPT; Wood, Janine PT, DPT; Roman, Carolyn A. PT; Hecker, Eva PT; Meffert, Marianne PT; Léveillé, Maude PT; Kienitz, Krista OTR, CHT, CLT; Swoboda, Kathryn J. MD

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Purpose: This study examined the reliability and validity of the Test of Infant Motor Performance Screening Items (TIMPSI) in infants with type I spinal muscular atrophy (SMA).

Methods: After training, 12 evaluators scored 4 videos of infants with type I SMA to assess interrater reliability. Intrarater and test-retest reliability was further assessed for 9 evaluators during a SMA type I clinical trial, with 9 evaluators testing a total of 38 infants twice. Relatedness of the TIMPSI score to ability to reach and ventilatory support was also examined.

Results: Excellent interrater video score reliability was noted (intraclass correlation coefficient, 0.97–0.98). Intrarater reliability was excellent (intraclass correlation coefficient, 0.91–0.98) and test-retest reliability ranged from r = 0.82 to r = 0.95. The TIMPSI score was related to the ability to reach (P ≤ .05).

Conclusion: The TIMPSI can reliably be used to assess motor function in infants with type I SMA. In addition, the TIMPSI scores are related to the ability to reach, an important functional skill in children with type I SMA.

© 2013 Lippincott Williams & Wilkins, Inc.


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