Pediatric Physical Therapy

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Pediatric Physical Therapy:
doi: 10.1097/PEP.0b013e318208ca9e
Research Article

Supramaximal Verification of Peak Oxygen Uptake in Adolescents With Cystic Fibrosis

Werkman, Maarten S. PT, MSc; Hulzebos, Hendrik J. PT, PhD; van de Weert-van Leeuwen, Pauline B. MSc, MD; Arets, Hubertus G.M. PhD, MD; Helders, Paul J.M. PT, PhD; Takken, Tim PhD

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Abstract

Purpose: To study whether peak oxygen uptake (

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O2 peak), attained in traditional cardiopulmonary exercise testing (CPET) in adolescents with cystic fibrosis (CF), could be verified by a supramaximal exercise test.

Methods: Sixteen adolescents with CF (forced expiratory volume in 1 second as % of predicted [range, 45%-117%]) volunteered and successively performed CPET and a supramaximal test (Steep Ramp Test [SRT] protocol).

Results: Cardiopulmonary exercise testing and the SRT resulted in comparable cardiorespiratory peak values. We found no significant difference in oxygen uptake (

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O2 peak/kg) between CPET and the SRT (38.9 ± 7.4 and 38.8 ± 8.5 mL min−1 kg−1, respectively; P = .81). We found no systemic bias for CPET and SRT measurements of

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O2 peak/kg and no differences between CPET and SRT

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O2 peak values within and between the maximal and non-maximal effort groups (P > .4).

Conclusion: The

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O2 peak measured in CPET seems to reflect the true

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O2 peak in adolescents with CF.

© 2011 Lippincott Williams & Wilkins, Inc.

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