Pediatric Emergency Care

Skip Navigation LinksHome > December 2012 - Volume 28 - Issue 12 > Ketamine, Propofol, and Ketofol Use for Pediatric Sedation
Pediatric Emergency Care:
doi: 10.1097/PEC.0b013e318276fde2
CME Review Article

Ketamine, Propofol, and Ketofol Use for Pediatric Sedation

Alletag, Michelle J. MD*; Auerbach, Marc A. MD, MSci; Baum, Carl R. MD, FAAP, FACMT

Continued Medical Education
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Abstract: The use of a combination of ketamine and propofol (ketofol) for procedural sedation and analgesia in the emergency department setting shows promise as an agent that may minimize adverse effects of ketamine or propofol as single agents. This article provides a summary of current literature regarding ketofol. It also reviews the comparative pharmacokinetics, adverse effects, and dosing of ketamine, propofol, and ketofol as agents for procedural sedation and analgesia.

© 2012 Lippincott Williams & Wilkins, Inc.


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