Pediatric Emergency Care

Skip Navigation LinksHome > June 2011 - Volume 27 - Issue 6 > Successful Intravenous Thrombolysis in a 14-Year-Old Boy Wit...
Pediatric Emergency Care:
doi: 10.1097/PEC.0b013e31821dc6e8
Illustrative Cases

Successful Intravenous Thrombolysis in a 14-Year-Old Boy With Ischemic Stroke

Sampaio, Isabel MD*; Abecasis, Francisco MD†; Quintas, Sofia MD‡; Moreno, Teresa MD‡; Camilo, Cristina MD†; Vieira, Marisa MD†; Pinho e Melo, Teresa MD§; Correia, Manuela MD†

Collapse Box

Abstract

Abstract: We report a healthy 14-year-old boy with an acute left middle cerebral artery stroke, treated 2 hours after the onset of symptoms with intravenous recombinant tissue plasminogen activator (r-TPA). Recanalization of the middle cerebral artery was documented with transcranial Doppler during the first 5 minutes of intravenous r-TPA perfusion, and progressive recovery of the neurological deficits occurred. Although lack of evidence regarding safety and efficacy in children precludes the recommendation of systematic use of r-TPA in pediatric stroke, we propose that this option should be considered and discussed with the parents, especially in older children presenting within 3 hours in centers with experience in adult thrombolysis.

© 2011 Lippincott Williams & Wilkins, Inc.

Login

Article Tools

Share

Article Level Metrics

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.