AJSP: Reviews & Reports

Skip Navigation LinksHome > July/August 2008 - Volume 13 - Issue 4 > Atypical Small Acinar Proliferation in the Prostate
Pathology Case Reviews:
doi: 10.1097/PCR.0b013e31817e18fa
Case Review

Atypical Small Acinar Proliferation in the Prostate

Meiers, Isabelle MD*; Kahane, Hillel MD, FCAP†; Bostwick, David G. MD, MBA, FCAP‡

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About 4% of contemporary prostate needle biopsies contain collections of small acini that are suspicious for cancer but which fall below the diagnostic threshold and are reported as atypical small acinar proliferation (ASAP) suspicious for but not diagnostic of malignancy. Prostate cancer has been identified in subsequent biopsies in the majority of cases of ASAP, indicating that this finding is a significant predictor of cancer. Identification of ASAP warrants repeat biopsy for concurrent or subsequent invasive carcinoma.

© 2008 Lippincott Williams & Wilkins, Inc.


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