You could be reading the full-text of this article now if you...

If you have access to this article through your institution,
you can view this article in

Nutrition and Age-Related Macular Degeneration: Research Evidence in Practice

Downie, Laura Elizabeth*; Keller, Peter Richard

Optometry & Vision Science:
doi: 10.1097/OPX.0000000000000285
Clinical Overview of Disease: Feature Review on Line
Abstract

ABSTRACT: Age-related macular degeneration (AMD) is the leading cause of irreversible visual impairment in developed countries. In the absence of effective treatments to slow AMD progression, it is predicted that the prevalence of AMD will double over the next 20 years. One area of significant interest is the potential role that nutrition may play in preventing and/or delaying the progression of AMD. Specifically, is there any benefit in oral antioxidant and/or mineral supplementation? This review critically evaluates the currently available evidence relating to nutrition and AMD, with particular reference to the key findings of two large National Eye Institute–sponsored clinical studies, namely, the Age-Related Eye Disease Study (AREDS) and AREDS2. Topical controversies relating to nutrition and AMD are considered and analyzed in the context of the published literature to guide practitioners through assessing the merit, or otherwise, of common claims. This article provides a foundation for clinicians to provide informed advice to AMD patients based on available research evidence.

Author Information

*PhD, BOptom, FAAO

BAppSc(Optom), PhD, PGCertOcTher, MBA, MHEth, FACO

The Department of Optometry and Vision Sciences, University of Melbourne, Victoria, Australia (all authors); and Macular Research Unit, Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia (PRK).

Laura Elizabeth Downie Lecturer and Clinical Leader Department of Optometry and Vision Sciences University of Melbourne Parkville, Victoria 3010 Australia e-mail: ldownie@unimelb.edu.au

© 2014 American Academy of Optometry