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Orthokeratology vs. Spectacles: Adverse Events and Discontinuations

Santodomingo-Rubido, Jacinto; Villa-Collar, César; Gilmartin, Bernard; Gutiérrez-Ortega, Ramón

doi: 10.1097/OPX.0b013e318263c5af
Original Articles

Purpose. To assess the relative clinical success of orthokeratology contact lenses (OK) and distance single-vision spectacles (SV) in children in terms of incidences of adverse events and discontinuations over a 2-year period.

Methods. Sixty-one subjects 6 to 12 years of age with myopia of − 0.75 to − 4.00DS and astigmatism ≤1.00DC were prospectively allocated OK or SV correction. Subjects were followed at 6-month intervals and advised to report to the clinic immediately should adverse events occur. Adverse events were categorized into serious, significant, and non-significant. Discontinuation was defined as cessation of lens wear for the remainder of the study.

Results. Thirty-one children were corrected with OK and 30 with SV. A higher incidence of adverse events was found with OK compared with SV (p < 0.001). Nine OK subjects experienced 16 adverse events (7 significant and 9 non-significant). No adverse events were found in the SV group. Most adverse events were found between 6 and 12 months of lens wear, with 11 solely attributable to OK wear. Significantly more discontinuations were found with SV in comparison with OK (p < 0.05).

Conclusions. The relatively low incidence of adverse events and discontinuations with OK is conducive for the correction of myopia in children with OK contact lenses.

*OD, PhD, MCOptom, FAAO

MSc, PhD, FAAO

PhD, FCOptom, FAAO

§MD, PhD

Menicon Co., Ltd. (Madrid Office), Madrid, Spain (JS-R), Clínica Oftalmológica Novovision, Madrid, Spain (CV-C; RG-O), Universidad Europea de Madrid, Madrid, Spain (CV-C), and School of Life and Health Sciences, Aston University, Aston Triangle, Birmingham, United Kingdom (BG).

Received January 19, 2012; accepted April 9, 2012.

Jacinto Santodomingo-Rubido Menicon Co., Ltd (Madrid Office) Iglesia 9, Apartamento 106 Majadahonda, Madrid, Spain e-mail: j.santodomingo@menicon.com

© 2012 American Academy of Optometry