You could be reading the full-text of this article now if you...

If you have access to this article through your institution,
you can view this article in

Ocular Problems in HIV and AIDS Patients in Nigeria

Emina, Michael Osita*; Odjimogho, Stella E.

Optometry & Vision Science:
doi: 10.1097/OPX.0b013e3181fef198
Original Article
Abstract

Purpose. To investigate ocular disease and visual acuity defects in patients with HIV/AIDS according to CD4+T-cells counts.

Methods. The CD4+T lymphocyte counts of all the volunteers were obtained. Visual acuity, refraction, ophthalmoscope, and slitlamp examinations were performed on each patient after the CD4+T-cell count result was obtained.

Results. Young adults aged between 21 and 30 years were mostly affected, 39 (97.5%) of the HIV patients had refractive errors, and 10 (25%) had reduced vision. Seven (17.5%) moderate and one (2.5%) severe low vision patients were found between 499 to 0 and 299 to 200 CD4+T-cell counts, respectively. Ocular diseases found in various CD4+T-cells counts were proptosis (2.5%), orbital cellulitis (2.5%), and cytomegalovirus retinitis (2.5%) in 99 to 0, keratoconjunctivitis sicca (2.5%) and corneal keratitis (2.5%) in 499 to 400, molluscum contagiosum (2.5%) in 299 to 200, iridocyclitis (2.5%) in 199 to 100, cloudy media (22.5%), red eyes (30%), poor pupillary reflexes (17.5%), and painful eye (30%) in 499 to 0, retinal exudates (15%), disc edema (30%), and choroidoretinitis (15%) in 399 to 0, ocular toxoplasmosis (5%) and herpes zoster (7.5%) in 299 to 100, Kaposi sarcoma (12.5%) in 199 to 0, conjunctivitis (7.5%) in 499 to 300, and uveitis (7.5%) in 399 to 200. There were significant differences between visual acuity of the control and the HIV/AIDS patients, p < 0.05.

Conclusions. Ocular impairments increased with decrease in CD4+T-cells counts. Additional studies are required in predicting the CD4+T-cells counts that will serve as a marker for specific ocular disease manifestation in HIV/AIDS.

Author Information

*OD, PhD

OD, MBA, FAAO

Department of Optometry, University of Benin, Benin City, Nigeria.

Received February 18, 2010; accepted August 23, 2010.

© 2010 American Academy of Optometry