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Prevalence and Characteristics of Peripheral Retinal Degeneration in Chinese Adults with High Myopia: A Cross-Sectional Prevalence Survey

LAM, DENNIS S. C. MD, FRCOphth; FAN, DOROTHY S. P. FRCS; CHAN, WAI-MAN MRCP, FRCS; TAM, BARBARA S. M. FRCS; KWOK, ALVIN K. H. MD, FRCS; LEUNG, ALFRED T. S. FRCS; PARSONS, HUGH MD, FRCSC

Original Article

Purpose. The purpose of this study was to study the prevalence of peripheral retinal findings in adult Chinese patients with high myopia (refraction ≤-6.00 D) and to investigate the correlation between the retinal lesions and the severity of myopia or axial length.

Methods. A cross-sectional prevalence survey screening was conducted in high ethnic Chinese myopes with refractions equal to or less than -6.00 D. The examinations included cycloplegic refraction, A and B scan ultrasonography, and retinal examinations by indirect ophthalmoscopy with scleral indentation and Goldmann three-mirror contact lens examination.

Results. Two hundred thirteen eyes in 213 patients with a mean refraction of -10.10 ± 4.23 D (range = -6.00 to -27.00 D) were examined. The mean axial length was 26.69 ± 1.68 mm (range = 25.18–33.62 mm) and the mean age was 33.5 ± 10.6 years (range = 18–73 years). The most common peripheral retinal finding was pigmentary degeneration (51.2%), followed by lattice degeneration in 12.2% and retinal holes in 7.5% of eyes. A positive correlation was noted between axial length and the lesions of pigmentary degeneration and pavingstone degeneration. The prevalence of retinal holes was 6.4% and 30.0% in eyes with axial length of <30 mm and ≥30 mm, respectively (chi-squared test, p = 0.006).

Conclusion. A high prevalence of peripheral retinal degenerations was found in adult Chinese high myopes. The presence of retinal holes was positively correlated with very high myopia of an axial length of ≥30 mm.

Department of Ophthalmology & Visual Sciences, The Chinese University of Hong Kong, Hong Kong Eye Hospital, Kowloon, Hong Kong, People’s Republic of China (DSCL, DSPF, WMC, AKHK,), the Department of Ophthalmology & Visual Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, People’s Republic of China (DSCL, DSPF, WMC, BSMT, ATSL, HP), the Department of Ophthalmology, Hong Kong Sanatorium and Hospital, Hong Kong, People’s Republic of China (AKHK), and the Outpatient Department, Hong Kong Baptist Hospital, Hong Kong, People’s Republic of China (ATSL)

Received April 5, 2004; accepted September 14, 2004.

© 2005 American Academy of Optometry