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Nuclear Medicine Communications:
doi: 10.1097/MNM.0000000000000191
Review article: PDF Only

Non-Alzheimer types of neurodegenerative dementia: clinical and 18F-FDG-PET/CT pictures.

Grassetto, Gaia; Marzola, Maria Cristina; Musto, Alessandra; Viniamury, Sobhan; Colletti, Patrick M.; Perkins, Alan C.; Rubello, Domenico

Published Ahead-of-Print
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Abstract

Primary degenerative dementia syndromes are an increasingly relevant problem worldwide because of the progressive aging of the population. Their diagnosis is often a challenge for clinicians and, even in the best cases, only a possible or probable diagnosis can be reached. Molecular neuroimaging techniques can be very useful in dementia patients, especially for obtaining a diagnosis in the early stage of disease. The most diffuse and widely available nuclear medicine method for neurological studies is 18F-fluoro-deoxy-glucose (18F-FDG)-PET, which allows the quantification of glucose gray matter metabolism and helps visualize typical, adequately specific, patterns for many kinds of degenerative dementia, not only for the well-known and well-studied Alzheimer's disease. This paper aims to describe the clinical and 18F-FDG-PET profiles of the principal non-Alzheimer type of degenerative dementias.

(C) 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins

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