Clinical Nuclear Medicine

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Clinical Nuclear Medicine:
doi: 10.1097/RLU.0b013e31825b23d5
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Superscan-like Hypermetabolic Lesions on Delayed FDG PET/CT Imaging in a Patient With Lung Cancer

Cheng, Gang MD, PhD*; Alavi, Abass MD (Hon), PhD (Hon), DSc (Hon); Lim, Esther MD*; Akers, Scott R. MD, PhD*

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From the *Department of Radiology, Philadelphia VA Medical Center; and †Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA.

Received for publication January 31, 2012; revision accepted March 6, 2012.

Conflicts of interest and sources of funding: none declared.

Reprints: Scott R. Akers, MD, PhD, Department of Radiology, Philadelphia VA Medical Center, 3900 Woodland Ave, Philadelphia, PA 19104. E-mail:

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Abstract: A 69-year-old man with a lung mass underwent multiple-time-point FDG PET/CT imaging for diagnostic evaluation. The initial PET imaging (performed at 1 hour after tracer injection) revealed equivocal bone marrow uptake in the right iliac bone and proximal femurs in addition to lung and mediastinal lesions. The 3-hour delayed PET imaging, however, demonstrated widespread bone marrow metastases. Biopsies of the right lung mass and right iliac bone marrow were later performed and revealed a poorly differentiated squamous cell carcinoma in both sites. This case indicates the value of delayed FDG PET in detecting superscan-like hypermetabolic bone marrow lesions in patients with lung cancer.

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FDG PET/CT; superscan; bone marrow metastasis; lung cancer

© 2012 Lippincott Williams & Wilkins, Inc.


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