Abstract: A 69-year-old man with a lung mass underwent multiple-time-point FDG PET/CT imaging for diagnostic evaluation. The initial PET imaging (performed at 1 hour after tracer injection) revealed equivocal bone marrow uptake in the right iliac bone and proximal femurs in addition to lung and mediastinal lesions. The 3-hour delayed PET imaging, however, demonstrated widespread bone marrow metastases. Biopsies of the right lung mass and right iliac bone marrow were later performed and revealed a poorly differentiated squamous cell carcinoma in both sites. This case indicates the value of delayed FDG PET in detecting superscan-like hypermetabolic bone marrow lesions in patients with lung cancer.
From the *Department of Radiology, Philadelphia VA Medical Center; and †Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA.
Received for publication January 31, 2012; revision accepted March 6, 2012.
Conflicts of interest and sources of funding: none declared.
Reprints: Scott R. Akers, MD, PhD, Department of Radiology, Philadelphia VA Medical Center, 3900 Woodland Ave, Philadelphia, PA 19104. E-mail: Scott.Akers@va.gov.