Recurrent Glioma and Crossed Cerebellar Diaschisis in a Patient Examined With 18F-DOPA and 18F-FDG PET/CT

Calabria, Ferdinando MD,*; Schillaci, Orazio MD*†

Clinical Nuclear Medicine:
doi: 10.1097/RLU.0b013e318262af2a
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Abstract: Two years after resection of a left parietal glioma, a 46-year-old woman underwent 18F-FDG and 18F-DOPA brain PET/CT. FDG showed left parietal hypometabolism with crossed cerebellar diaschisis. No abnormally increased FDG activity was seen. 18F-DOPA PET/CT scan demonstrated focal left parietal uptake. Recurrent glioma was confirmed by surgical biopsy. 18F-DOPA may demonstrate abnormal amino acid metabolism in evaluation of recurrence of glioma.

Author Information

From the *Department of Nuclear Medicine and Molecular Imaging, IRCCS Neuromed, Pozzilli (IS); and †Department of Biopathology and Diagnostic Imaging, University “Tor Vergata,” Rome, Italy.

Received for publication February 16, 2012; revision accepted May 30, 2012.

Conflicts of interest and sources of funding: none declared.

Reprints: Ferdinando Calabria, MD, Department of Nuclear Medicine and Molecular Imaging, IRCCS Neuromed, Via Atinense 18, 86077 Pozzilli (IS), Italy. E-mail:

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18F-DOPA; 18F-FDG; PET/CT; brain tumor recurrence; crossed cerebellar diaschisis

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