An Unusual 131I-Avid Adrenal Metastasis From Follicular Thyroid Carcinoma Identified by 131I-SPECT/CT

Xue, Yan-Li MD*†; Song, Hong-Jun MD*; Qiu, Zhong-Ling MD*; Luo, Quan-Yong MD*

Clinical Nuclear Medicine:
doi: 10.1097/RLU.0b013e318262addb
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Abstract: The adrenal gland is an uncommon site of metastasis from differentiated thyroid carcinoma, and 131I-avid adrenal metastatic lesions are even rarer. Here, we describe a 54-year-old woman with 131I-avid adrenal metastasis from follicular thyroid carcinoma identified using 131I whole-body scan (131I-WBS) and 131I-SPECT/CT. 131I-SPECT/CT allowed superior localization of the equivocal 131I uptake in the 131I-WBS. It provides metabolic and anatomic information about a lesion, resulting in accurate localization and improved definition of 131I-WBS findings.

Author Information

From the *Department of Nuclear Medicine, Shanghai Sixth People’s Hospital, Shanghai Jiao Tong University, Shanghai; and †Department, Soochow University, Suzhou, China.

Received for publication December 7, 2011; and revision accepted April 23, 2012.

Conflicts of interest and sources of funding: none declared.

Reprints: Quan-Yong Luo, MD, Department of Nuclear Medicine, Shanghai Sixth People’s Hospital, Shanghai Jiao Tong University, 600 Yishan Rd, Shanghai 200233, China. E-mail:

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differentiated thyroid carcinoma; adrenal metastasis; radioiodine therapy; SPECT/CT

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