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Clinical Nuclear Medicine:
doi: 10.1097/RLU.0b013e31829af8c0
Review Article

Role of SPECT/CT in Sentinel Lymph Node Detection in Patients With Breast Cancer

Vercellino, Laetitia MD*†; Ohnona, Jessica MD*†; Groheux, David MD, PhD*†; Slama, Abdelhak MD*†; Colletti, Patrick M. MD; Chondrogiannis, Sotirios MD§; Merlet, Pascal MD*†; Toubert, Marie-Elisabeth MD*†; Rubello, Domenico MD§

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Abstract

Aim

The purpose of this study was to conduct a systematic review of the published literature to assess the role (indications, advantages, and limitations) of SPECT/CT for the detection of sentinel lymph node (SLN) in breast cancer.

Methods

The authors searched PubMed for published literature in English addressing this topic.

Results

Eleven studies, published since 2006, focused on the role and value of SPECT/CT for SLN detection (SLND). They showed that SPECT/CT improved sentinel node detection and anatomical localization. One study suggested that SPECT/CT may provide a more accurate staging. Limitations for SLND with SPECT/CT include extra time and inconvenience for the patient and additional radiation dose.

Conclusions

SPECT/CT is a valuable tool for SLND, especially in difficult cases, when planar lymphoscintigraphy shows no SLN or unexpected lymphatic drainage.

Copyright © 2013 by Lippincott Williams & Wilkins

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