Skip Navigation LinksHome > May 2014 - Volume 39 - Issue 5 > Peptide Receptor Radionuclide Therapy With 177Lu DOTATATE in...
Clinical Nuclear Medicine:
doi: 10.1097/RLU.0000000000000273
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Peptide Receptor Radionuclide Therapy With 177Lu DOTATATE in a Case of Recurrent Carotid Body Paraganglioma With Spinal Metastases

Gupta, Santosh Kumar MSc; Singla, Suhas MD; Karunanithi, Sellam MD; Damle, Nishikant MD; Bal, Chandrasekhar MD, DSc (HC)

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Abstract

Abstract: Paragangliomas are rare benign neuroendocrine tumors, and 80% of all paragangliomas are either carotid body tumors or glomus jugulare tumors. We present a case of recurrent unresectable carotid body paraganglioma with nodal and T7 vertebral metastases in a 30-year-old man 6 years postsurgery detected with 68Ga DOTANOC PET/CT and was administered with peptide receptor radionuclide therapy using 177Lu DOTATATE. After 5 cycles of 177Lu DOTATATE (total cumulative activity of 750 mCi [27 GBq]), significant response at the primary site on 68Ga DOTANOC PET/CT and complete disappearance of nodal and T7 vertebral metastases were noted.

© 2014 by Lippincott Williams & Wilkins

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