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Focal Thoracic Uptake Mimicking Lung Metastasis on 131I Post-Therapy Whole-Body Scan in Patients With Thyroid Carcinoma

Jia, Changping MD, PhD; Moadel, Renee MD; Freeman, Leonard M. MD

Clinical Nuclear Medicine:
doi: 10.1097/RLU.0b013e31829959ce
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Abstract: Whole-body 131I scan after total thyroidectomy is important in the evaluation of radioiodine avid metastatic foci in patients with differentiated thyroid carcinoma. False-positive uptakes are occasionally seen in the thoracic region which should be evaluated carefully and not mistaken as lung metastases. We report here 2 cases of abnormal focal thoracic uptake, 1 case of a pleuropericardial cyst and 1 case of focal bronchiectasis, that could potentially be confused with lung metastasis. Careful correlation with diagnostic CT and subsequent follow-up studies suggested that these were not metastatic lesions.

Author Information

From the Division of Nuclear Medicine, Department of Radiology, Montefiore Medical Center and Albert Einstein College of Medicine, Bronx, NY.

Received for publication December 7, 2012; revision accepted April 6, 2013.

Conflicts of interest and sources of funding: none declared.

Reprints: Leonard M. Freeman, MD, Division of Nuclear Medicine, Department of Radiology, Montefiore Medical Center, 111 East 210th Street, Bronx, NY 10467. E-mail:

© 2014 by Lippincott Williams & Wilkins