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18F-FDG PET/CT Imaging Features of Rosai Dorfman Disease: A Rare Cause of Massive Generalized Lymphadenopathy

Karunanithi, Sellam MD; Singh, Harmandeep MD; Sharma, Punit MD; Naswa, Niraj MD; Kumar, Rakesh MD, PhD

doi: 10.1097/RLU.0b013e31828731da
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Rosai Dorfman disease (RDD) or sinus histiocytosis is a rare non-neoplastic idiopathic disease characterized by massive lymphadenopathy in young adults. Extranodal involvement is seen in 25%–43% cases. RDD is usually self-remitting. However, it mimics lymphoproliferatve disorders clinically as well as on imaging. We present the 18F-FDG PET/CT findings in a 46-year-old female patient with nodal RDD.

From the Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.

Received for publication November 26, 2012; revision accepted January 7, 2013.

Conflicts of interest and sources of funding: none declared.

Reprints: Rakesh Kumar, MD, PhD, Department of Nuclear Medicine, All India Institute of Medical Sciences, E-81, Ansari Nagar (East), AIIMS Campus, New Delhi 110029, India. E-mail: rkphulia@yahoo.com.

© 2014 by Lippincott Williams & Wilkins