This review article is focused on the role of FDG PET/CT in diagnosing and characterizing hepatic incidentalomas. A large variety of unsuspected lesions can be detected in the liver both with ultrasound and CT performed for other reasons; the prevalence of liver incidentalomas increases in patients with chronic liver disease or preexisting oncologic history. The major challenge is to discriminate benign from malignant lesions. There is a large body of literature indicating that FDG PET/CT is a useful tool to this purpose even if it is unspecific (ie, it cannot differentiate a primary tumor from a secondary lesion). Occasionally, FDG PET/CT can be useful for biopsy guidance.
From the Departments of *Nuclear Medicine, and †Surgery, Santa Maria della Misericordia Hospital, Rovigo, Italy; and ‡Department of Radiology, University of Southern California, Los Angeles, CA.
Received for publication September 3, 2013; revision accepted October 24, 2013.
Conflicts of interest and sources of funding: none declared.
Reprints: Gaia Grassetto, MD, Departments of Imaging, Radiology, Interventional Radiology, Neuroradiology, Nuclear Medicine, Service of Nuclear Medicine & PET/CT Centre, Santa Maria della Misericordia Hospital, Viale Tre Martiri 140, 45100 Rovigo, Italy. E-mail: firstname.lastname@example.org.