Clinical Nuclear Medicine

Skip Navigation LinksHome > January 2014 - Volume 39 - Issue 1 > Improved Detection of Sentinel Lymph Nodes in SPECT/CT Image...
Clinical Nuclear Medicine:
doi: 10.1097/RLU.0b013e31828da362
Original Articles

Improved Detection of Sentinel Lymph Nodes in SPECT/CT Images Acquired Using a Low- to Medium-Energy General-Purpose Collimator

Yoneyama, Hiroto PhD*; Tsushima, Hiroyuki PhD; Kobayashi, Masato PhD; Onoguchi, Masahisa PhD; Nakajima, Kenichi MD§; Kinuya, Seigo MD§

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Purpose: The use of the low-energy high-resolution (LEHR) collimator for lymphoscintigraphy causes the appearance of star-shaped artifacts at injection sites. The aim of this study was to confirm whether the lower resolution of the low- to medium-energy general-purpose (LMEGP) collimator is compensated by decrease in the degree of septal penetration and the reduction in star-shaped artifacts.

Methods: A total of 106 female patients with breast cancer, diagnosed by biopsy, were enrolled in this study. 99mTc phytate (37 MBq, 1 mCi) was injected around the tumor, and planar and SPECT/CT images were obtained after 3 to 4 hours. When sentinel lymph nodes (SLNs) could not be identified from planar and SPECT/CT images by using the LEHR collimator, we repeated the study with the LMEGP collimator.

Results: Planar imaging performed using the LEHR and LEHR + LMEGP collimators positively identified SLNs in 96.2% (102/106) and 99.1% (105/106) of the patients, respectively. Using combination of planar and SPECT/CT imaging with the LEHR and LEHR + LMEGP collimators, SLNs were positively identified in 97.2% (103/106) and 100% (106/106) of the patients, respectively.

Conclusions: The LMEGP collimator provided better results than the LEHR collimator because of the lower degree of septal penetration. The use of the LMEGP collimator improved SLN detection.

© 2014 by Lippincott Williams & Wilkins


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