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Metastatic Ovarian Carcinoma Showing Surprisingly Widespread Subcutaneous 99mTc-MDP Soft-Tissue Uptake

Sogbein, Oyebola O. PhD, MBBS; Pelletier-Galarneau, Matthieu MSc, MD; Pham, Xuan H. MD, FRCPSC

Clinical Nuclear Medicine:
doi: 10.1097/RLU.0b013e3182a23cdc
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Abstract: Cutaneous involvement is generally unusual for metastases in a variety of primary malignancies including patients diagnosed with ovarian cancer. We report the rare observance of subcutaneous lesions from an aggressive ovarian primary carcinoma with unusual uptake of 99mTc-MDP on a tomographic whole-body bone scan without osseous metastatic lesions or uptake. The findings were correlated with cross-sectional imaging in addition to histological analysis.

Author Information

From the Division of Nuclear Medicine, University of Ottawa, Ottawa, ON, Canada.

Received for publication September 20, 2012; and revision accepted June 11, 2013.

Conflicts of interest and sources of funding: none declared.

Reprints: Oyebola Sogbein, PhD, MBBS, Department of Nuclear Medicine, The Ottawa Hospital, General Campus, 501 Smyth Road, University of Ottawa, Ottawa, ON, Canada K1H 8L6. E-mail:

© 2013 by Lippincott Williams & Wilkins