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Combined 18F-FDG PET/CT and 99mTc 3PRGD2 SPECT/CT Imaging in a Case of Pituitary Metastases

Hou, Yuantao MD; Zhu, Zhaohui MD*; Jin, Xiaona MD*; Wang, Renzhi MD; Xing, Bing MD

doi: 10.1097/RLU.0b013e318292aa2f
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Abstract: We compare 18F-FDG PET/CT and 99mTc 3PRGD2 SPECT/CT scans in a case of histologically proved pituitary metastases. The ratio of tumor to cerebellum (T/C) of 99mTc 3PRGD2 SPECT is much higher than that for 18F-FDG PET. We then conduct the same scans for a pituitary adenoma patient for better comparison. The T/C of 18F-FDG is not able to differentiate pituitary metastases from pituitary adenoma. However, The T/C of 99mTc 3PRGD2 observed in pituitary metastases was higher than that in pituitary adenoma.

From the *Department of Nuclear Medicine and †Key Laboratory of Endocrinology, Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Received for publication August 4, 2012; revision accepted March 1, 2013.

Conflicts of interest and sources of funding: none declared.

Reprints: Bing Xing, MD, Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Dong-dan Street, Beijing 100730, China. E-mail: xingbingemail@yahoo.com.cn.

© 2013 by Lippincott Williams & Wilkins