Clinical Nuclear Medicine

Skip Navigation LinksHome > April 2013 - Volume 38 - Issue 4 > Comparison of 18F-FDG PET/CT and 68Ga-DOTATATE PET/CT Imagin...
Clinical Nuclear Medicine:
doi: 10.1097/RLU.0b013e318281658e
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Comparison of 18F-FDG PET/CT and 68Ga-DOTATATE PET/CT Imaging in Metastasized Merkel Cell Carcinoma

Epstude, Maximilian MD*; Tornquist, Katharina MD*; Riklin, Christian MD; di Lenardo, Francesca MD; Winterhalder, Ralph MD; Hug, Urs MD§; Strobel, Klaus MD*

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Abstract: Merkel cell carcinoma (MCC) is a rare but very aggressive neuroendocrine tumor of the skin in elderly patients with higher mortality compared with melanoma. No evidence-based standardized chemotherapy exists for metastasized patients.

We report the case of an 87-year-old patient with the history of resection of a large MCC of the parietal scalp planned for radiotherapy and staged with FDG PET/CT showing disseminated distant metastases. 68Ga-DOTATATE PET/CT revealed more extensive tumor load compared with FDG, and due to the intensive expression of somatostatin receptors the patient qualified for 90Y DOTATOC therapy.

© 2013 by Lippincott Williams & Wilkins


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