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Papillary Carcinoma Thyroid With Uveal Metastases

Padma, S. MBBS, DRM; Tiwari, Anshu MBBS; Borde, Chaitanya R. MBBS, DRM; G. S., Shagos MBBS, DRM, DNB; Palaniswamy, Shanmuga Sundaram MBBS, DRM, DNB, MNAMS

Clinical Nuclear Medicine:
doi: 10.1097/RLU.0b013e31827a2275
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Abstract: Ocular metastases secondary to thyroid cancer are extremely uncommon, typically affecting the orbit rather than the globe and uvea. Within the uveal structures, the choroid is more commonly involved than the iris and ciliary body. We present a 56-year-old male patient who underwent total thyroidectomy for metastatic papillary thyroid carcinoma (PTC), solid variant. Whole-body 131I (WBI) scintigraphy was performed and the patient was treated twice with high-dose 131I therapy. WBI after the second treatment demonstrated right orbital activity. The patient developed sudden onset of right eye diminished vision and was diagnosed with uveal (choroidal) metastases from PTC.

Author Information

From the Department of Nuclear Medicine & PET CT, Amrita Institute of Medical Sciences, Cochin 6802041, Kerala, India.

Received for publication March 16, 2012; revision accepted October 15, 2012.

Conflicts of interest and sources of funding: none declared.

Reprints: S. Padma, MBBS, DRM, Department of Nuclear Medicine & PET CT, Amrita Institute of Medical Sciences, Cochin, Kerala, India. E-mail:

© 2013 Lippincott Williams & Wilkins, Inc.