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Osteoblastoma of the Mandible Mimicking Osteosarcoma in FDG PET/CT Imaging

Strobel, Klaus MD*; Merwald, Michael MD; Huellner, Martin MD*; Zenklusen, Hans R. MD; Kuttenberger, Johannes MD

Clinical Nuclear Medicine:
doi: 10.1097/RLU.0b013e318279f131
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Abstract: Osteoblastomas are rare tumors accounting for approximately 1% of all primary bone tumors. We report a case of osteoblastoma of the mandible with high FDG uptake. Initially, this lesion was judged as an osteosarcoma. Osteoblastomas are benign slow-growing tumors. High-resolution thin-slice CT images of the lesion as part of the PET/CT study help to characterize its morphology and extension, thus facilitating biopsy planning and resection. Approximately 25% of osteoblastomas initially have the imaging appearance of a malignant tumor. In our case, complete resection of the lesion followed by reconstruction with a bone graft was performed.

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From the *Department of Nuclear Medicine and Radiology, †Department of Oral and Maxillofacial Surgery, and ‡Department of Pathology, Cantonal Hospital Lucerne, Lucerne, Switzerland.

Received for publication June 8, 2012; revision accepted September 12, 2012.

Conflicts of interest and sources of funding: none declared.

Reprints: Klaus Strobel, MD, Department of Nuclear Medicine and Radiology, Cantonal Hospital Lucerne, CH 6000 Lucerne 16, Switzerland. E-mail:

© 2013 Lippincott Williams & Wilkins, Inc.