Clinical Nuclear Medicine

Skip Navigation LinksHome > February 2013 - Volume 38 - Issue 2 > Efficacy of Heparin Loading During an 18F-FDG PET/CT Examina...
Clinical Nuclear Medicine:
doi: 10.1097/RLU.0b013e318266cb25
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Efficacy of Heparin Loading During an 18F-FDG PET/CT Examination to Search for Cardiac Sarcoidosis Activity

Ito, Kimiteru MD, PhD*; Morooka, Miyako MD, PhD; Okazaki, Osamu MD; Minaminoto, Ryogo MD, PhD; Kubota, Kazuo MD, PhD; Hiroe, Michiaki MD, PhD

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Abstract

Abstract: A 65-year-old woman with a complete atrioventricular block was diagnosed as having cardiac sarcoidosis. 18F-FDG PET/CT imaging without unfractionated heparin loading revealed systemic abnormal uptake indicating sarcoidosis. However, the cardiac lesions were vague because of the physiological FDG uptake. One month later, 18F-FDG PET/CT using heparin loading was performed to evaluate the lesion activity prior to the start of steroid administration. 18F-FDG PET/CT imaging with heparin loading showed the cardiac lesions more clearly and suppressed the FDG uptake in normal myocardium. Heparin loading during FDG PET/CT may be useful for detecting cardiac involvement in patients with cardiac sarcoidosis.

© 2013 Lippincott Williams & Wilkins, Inc.

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