Abstract: Bone scintigraphy has been used extensively in prostate cancer patients to detect bone involvement.
11C-choline PET/CT is indicated when a biochemical recurrence is suspected, as this procedure is able to detect local recurrence, lymph-node infiltration, and metastases.
In cases where the results of these 2 procedures do not coincide, MRI is then usually performed. 18F-fluoride may become an alternative to MRI for bone imaging.
In our patient series, all bone lesions with 11C-choline uptake were metastases. 18F-Fluoride did not increase specificity of 11C-choline but increased sensitivity of bone scintigraphy. CT helped in the interpretation of osteoarthritis and trauma lesions.