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Bone Metastases from Prostate Cancer: 18F-Fluoride PET/CT in a Patient With Discordant Bone Scintigraphy and 11C-Choline PET/CT

Garcia, Garzon Jr MD; Riera, Eduard MD; Valls, Eulalia MD; Soler, Marina MD; Bassa, Pere MD; Moragas, Merce MD; Lomeña, Francisco MD

doi: 10.1097/RLU.0b013e31827a20d3
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Abstract: Bone scintigraphy has been used extensively in prostate cancer patients to detect bone involvement.

11C-choline PET/CT is indicated when a biochemical recurrence is suspected, as this procedure is able to detect local recurrence, lymph-node infiltration, and metastases.

In cases where the results of these 2 procedures do not coincide, MRI is then usually performed. 18F-fluoride may become an alternative to MRI for bone imaging.

In our patient series, all bone lesions with 11C-choline uptake were metastases. 18F-Fluoride did not increase specificity of 11C-choline but increased sensitivity of bone scintigraphy. CT helped in the interpretation of osteoarthritis and trauma lesions.

From the Unidad PET/TC CETIR-ERESA, 08950 Esplugues de Llobregat, Barcelona, Spain.

Received for publication November 21, 2011; revision accepted October 15, 2012.

Conflicts of interest and sources of funding: none declared.

Reprints: Garzon Garcia Jr, MD, Unidad PET/TC CETIR-ERESA, C/J Anselm Clave 100, 08950 Esplugues de Llobregat, Barcelona, Spain. E-mail: jrgarcia@cetir.es.

© 2013 Lippincott Williams & Wilkins, Inc.