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Diffuse Homogeneous Bone Marrow Uptake of FDG in Patients With Acute Lymphoblastic Leukemia

Su, Kanae MD; Nakamoto, Yuji MD, PhD; Nakatani, Koya MD; Kurihara, Kensuke MD; Hayakawa, Nobuyuki MD; Togashi, Kaori MD, PhD

doi: 10.1097/RLU.0b013e3182485277
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Abstract: PET (positron emission tomography) using FDG (18F-fluorodeoxyglucose) has been widely used in the evaluation of various malignancies, but its clinical application to leukemia remains limited. We report a case of leukemia in which diffuse bone marrow uptake of FDG was observed, and bone marrow aspiration subsequently revealed acute lymphoblastic leukemia. It is not easy to differentiate between physiological and pathologic uptake when diffuse homogeneous uptake in bone marrow is observed.

From the Department of Diagnostic Radiology, Kyoto University Hospital, Kyoto, Japan.

Received for publication September 15, 2011; accepted December 26, 2011.

Conflicts of interest and sources of funding: none declared.

Reprints: Yuji Nakamoto, MD, PhD, Department of Diagnostic Radiology, Kyoto University Hospital, 54 Shogoinkawahara-cho, Sakyo-ku, Kyoto 606–8507, Japan. E-mail: ynakamo1@kuhp.kyoto-u.ac.jp.

© 2013 Lippincott Williams & Wilkins, Inc.