We report the usefulness of 18F-FDG PET/CT for the detection and therapy evaluation of the infective vegetation. A 64-year-old man with history of aortic valve replacement presented with 2 months of fever without identifiable cause. Echocardiogram showed no inflammation vegetation or abnormality of mechanical valve function. FDG PET/CT with 50 IU/kg IV heparin revealed focal uptakes near the mechanical aortic valve. After antibiotics therapy, fever was ameliorated, and FDG PET/CT findings showed markedly decreased uptake of the lesions. FDG PET/CT is a powerful tool to detect endocarditis even in patients with no anatomical abnormalities.
From the *Department of Radiology, Faculty of Medicine Chiang Mai University, Chiang Mai, Thailand; †Department of Nuclear Medicine, Hokkaido University Graduate School of Medicine; and Departments of ‡Diagnostic and Interventional Radiology and §Cardiovascular Medicine, Hokkaido University Hospital, Sapporo, Japan.
Received for publication December 21, 2011; revision accepted February 21, 2012.
Conflicts of interest and sources of funding: none declared.
Reprints: Noriko Oyama-Manabe, MD, PhD, Department of Diagnostic and Interventional Radiology, Hokkaido University Hospital, N15 W7, kita-ku, Sapporo 060-8638, Japan. E-mail: firstname.lastname@example.org.