Skip Navigation LinksHome > September 2012 - Volume 37 - Issue 9 > Ictal and Interictal 99mTc-HMPAO Brain SPECT of a MELAS Case...
Clinical Nuclear Medicine:
doi: 10.1097/RLU.0b013e318262ad48
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Ictal and Interictal 99mTc-HMPAO Brain SPECT of a MELAS Case Presented With Epilepsy-like Visual Hallucination

Wei, Cheng-Yu MD*†; Hsiao, Heng-Long MD; Chen, Shang-Chi MD§; Hung, Guang-Uei MD∥¶; Kao, Chia-Hung MD

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Abstract: A 55-year-old woman was diagnosed with the syndrome of mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS). She was referred for 99mTc-HMPAO brain SPECT because of visual hallucinations, which were suspected to be related to epileptic seizures. Ictal SPECT images showed remarkable hyperperfusion in the left occipital cortex, which returned to near-normal status on the interictal SPECT images after treatment with anticonvulsants. It is very rare to see such an ictal SPECT image of epileptic or epilepsy-like disorders, especially in the setting of MELAS syndrome with visual hallucination.

© 2012 Lippincott Williams & Wilkins, Inc.


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