Skip Navigation LinksHome > September 2012 - Volume 37 - Issue 9 > 18F-DOPA PET/CT But Not 68Ga-DOTA-TOC PET/CT Revealed the Un...
Clinical Nuclear Medicine:
doi: 10.1097/RLU.0b013e318262adc7
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18F-DOPA PET/CT But Not 68Ga-DOTA-TOC PET/CT Revealed the Underlying Cause of Ectopic Cushing Syndrome

Schalin-Jäntti, Camilla PhD, MD*†; Ahonen, Aapo PhD, MD‡§; Seppänen, Marko PhD, MD

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Abstract

Abstract: 18F-DOPA PET/CT but not 68Ga-DOTA-TOC PET/CT revealed the cause of ectopic Cushing syndrome in a 61-year-old man. The patient presented with rapid weight gain, swollen legs, and sleep disturbances. Plasma potassium level was 2.7 mM (reference range, 3.3–4.9 mM), 24-hour urinary cortisol level was 13,124 nmol (reference range, 30–144 nmol), and plasma adrenocorticotropin level was 61 ng/L (reference range, <48 g/L). CT demonstrated prominent lymph nodes in the left lung hilus and hyperplastic adrenals but no primary tumor. 68Ga-DOTA-TOC PET/CT, which is recommended as the first-line PET imaging, was performed, but it was not diagnostic. Imaging with 18F-DOPA PET/CT revealed the underlying cause.

© 2012 Lippincott Williams & Wilkins, Inc.

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