Clinical Nuclear Medicine

Skip Navigation LinksHome > August 2012 - Volume 37 - Issue 8 > 18F-FDG PET Detection of Unknown Primary Malignancy in Derma...
Clinical Nuclear Medicine:
doi: 10.1097/RLU.0b013e318252d22a
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18F-FDG PET Detection of Unknown Primary Malignancy in Dermatomyositis

Mahmood, Syed MD*†; Rodríguez Martínez de Llano, Sofia MD, PhD

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Abstract: Dermatomyositis is an inflammatory myopathy that has an association with malignancy in adults. We present a patient who initially presented with adenopathy and progressive muscular weakness and was diagnosed with dermatomyositis and lung carcinoma on further investigation. Whole-body PET/CT scan revealed diffuse proximal muscle hypermetabolism representing the inflammatory nature of dermatomyositis, and an intensely FDG-avid primary right lower lung small cell lung carcinoma and metastatic thoracic lymphadenopathy. PET/CT imaging may offer an “all-in-one” procedure as an alternative to other diagnostic procedures, reducing the number of unnecessary investigations in patients presenting with paraneoplastic syndromes searching for underlying malignancy.

© 2012 Lippincott Williams & Wilkins, Inc.


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