Sodium fluoride (NaF) is a bone-seeking positron-emitting tracer with high sensitivity and specificity for detection of osseous lesions, particularly osteolytic lesions. We believe that NaF positron emission tomography (PET)/computed tomography (CT) scans can provide a more thorough and conclusive evaluation of bone diseases than conventional Technetium-99m-methylene diphosphonate bone scans. Understanding both normal and pathologic patterns is important for the evaluation and interpretation of these studies. Thus, an atlas of NaF positron emission tomography/computed tomography bone scans demonstrating benign, pathologic, and malignant osseous lesions as well as extraosseous lesions will be invaluable in the correct interpretation and diagnosis of osseous lesions.
From the Division of Nuclear Medicine, Department of Radiology, Keck School of Medicine University of Southern California, Los Angeles, CA.
Received for publication November 9, 2011; revision accepted January 22, 2012.
Conflicts of interest and sources of funding: none declared.
Reprints: Sindu Sheth, MD, University of Southern California, 1510 San Pablo Street, Suite 350, Los Angeles, CA 90033. E-mail: firstname.lastname@example.org.