Clinical Nuclear Medicine

Skip Navigation LinksHome > March 2012 - Volume 37 - Issue 3 > 111In OctreoScan SPECT-MRI Fusion for the Detection of a Pan...
Clinical Nuclear Medicine:
doi: 10.1097/RLU.0b013e31823ea402
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111In OctreoScan SPECT-MRI Fusion for the Detection of a Pancreatic Insulinoma

Moncayo, Valeria M. MD*,†; Martin, Diego R. MD*; Sarmiento, Juan M. MD; Zbytek, Blazej MD§; Fox, Tim PhD; Schuster, David M. MD*,†

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Abstract

A 72-year-old woman with a history of diabetes mellitus presented with severe episodes of hypoglycemia, associated with diaphoresis and somnolence, for 1 year. Workup revealed high insulin and c-peptide. Given the clinical suspicion of an insulinoma, an MRI was performed, which demonstrated abnormal enhancement in the pancreatic head. An octreotide scan with combined single-photon emission computed tomography–computed tomography was performed and fused to the MR, which identified radiotracer uptake at the site of the MR enhancement, enabling precise localization of a pancreatic somatostatin receptor–avid tumor. The patient underwent tumor enucleation with pancreatojejunostomy, and pathologic tests confirmed an insulinoma.

© 2012 Lippincott Williams & Wilkins, Inc.

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